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1

ChemInform Abstract: Mild Decarboxylative Activation of Malonic Acid Derivatives by 1,1′-Carbonyldiimidazole.

Danny Lafrance, Paul Bowles, Kyle Leeman, Robert Rafka

Journal:

Year:

2011

File:

PDF, 40 KB

2011

2

Synthesis of 4-seleno-d-fructose derivatives and an investigation of their utility as precursors of unsaturated hexulofuranosides

Olivier R. Martin, Robert J. Rafka, Walter A. Szarek

Journal:

Carbohydrate Research

Year:

1989

Language:

english

File:

PDF, 1020 KB

english, 1989

3

A facile isolation of 2,5-anhydro-l-iditol

Robert J. Rafka, Barry J. Morton

Journal:

Carbohydrate Research

Year:

1994

Language:

english

File:

PDF, 265 KB

english, 1994

4

In vitro and in vivo profile of 2-(3-di-fluoromethyl-5-phenylpyrazol-1-yl)-5-methanesulfonylpyridine, a potent, selective, and orally active canine COX-2 inhibitor

Jin Li, Michael P. Lynch, Kristin Lundy DeMello, Subas M. Sakya, Hengmiao Cheng, Robert J. Rafka, Brian S. Bronk, Burton H. Jaynes, Carolyn Kilroy, Donald W. Mann, Michelle L. Haven, Nicole L. Kolosko

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 139 KB

english, 2005

5

Discovery of a potent, selective and orally active canine COX-2 inhibitor, 2-(3-difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl-pyridine

Jin Li, Kristin M.Lundy DeMello, Henry Cheng, Subas M. Sakya, Brian S. Bronk, Robert J. Rafka, Burton H. Jaynes, Carl B. Ziegler, Carolyn Kilroy, Donald W. Mann, Eric L. Nimz, Michael P. Lynch, Michel

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 200 KB

english, 2004

6

5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part 1: Structure–activity relationship studies of 5-alkylamino pyrazoles and discovery of a potent, selective, and orally active analog

Subas M. Sakya, Kristin M. Lundy DeMello, Martha L. Minich, Bryson Rast, Andrei Shavnya, Robert J. Rafka, David A. Koss, Hengmiao Cheng, Jin Li, Burton H. Jaynes, Carl B. Ziegler, Donald W. Mann, Caro

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 157 KB

english, 2006

7

5-Heteroatom-substituted pyrazoles as canine COX-2 inhibitors: Part 2. Structure–activity relationship studies of 5-alkylethers and 5-thioethers

Subas M. Sakya, Hengmiao Cheng, Kristin M. Lundy DeMello, Andrei Shavnya, Martha L. Minich, Bryson Rast, Jason Dutra, Chao Li, Robert J. Rafka, David A. Koss, Jin Li, Burton H. Jaynes, Carl B. Ziegler

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 158 KB

english, 2006

8

Synthesis and SAR of heteroaryl-phenyl-substituted pyrazole derivatives as highly selective and potent canine COX-2 inhibitors

Hengmiao Cheng, Kristin M. Lundy DeMello, Jin Li, Subas M. Sakya, Kazuo Ando, K. Kawamura, Tomoki Kato, Robert J. Rafka, Burton H. Jaynes, Carl B. Ziegler, Rod Stevens, Lisa A. Lund, Donald W. Mann, C

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 153 KB

english, 2006

9

The Immune System, the Skin, and Childhood Rheumatic Disease

Robert C. Fuhlbrigge, Rafka Chaiban

Journal:

Current Rheumatology Reports

Year:

2011

Language:

english

File:

PDF, 263 KB

english, 2011

10

Mild Decarboxylative Activation of Malonic Acid Derivatives by 1,1′-Carbonyldiimidazole

Lafrance, Danny, Bowles, Paul, Leeman, Kyle, Rafka, Robert

Journal:

Organic Letters

Year:

2011

Language:

english

File:

PDF, 860 KB

english, 2011

11

Structure–sweetness relationships for fructose analogs. Part III. 3-Deoxy- D - erythro -hexulose (3-deoxy- D -fructose): composition in solution and evaluation of sweetness

Szarek, Walter A., Rafka, Robert J., Yang, Te-Fang, Martin, Olivier R.

Journal:

Canadian Journal of Chemistry

Year:

1995

Language:

english

File:

PDF, 384 KB

english, 1995

12

Structure–sweetness relationships for fructose analogs. Part II. Synthesis and properties of 1,6-dihydroxy-2-hexanone, a simple analog of the ketohexoses, and X-ray structure determination of the corresponding dianhydrides

Szarek, Walter A., Martin, Olivier R., Rafka, Robert J., Cameron, T. Stanley

Journal:

Canadian Journal of Chemistry

Year:

1985

Language:

english

File:

PDF, 378 KB

english, 1985

13

Enabled Process To Synthesize Monobactam 1 for Early Development

Tao, Yong, Lall, Manjinder S., Boyles, David C., Lilley, Susan C., Pattavina, Sebastian D., Rafka, Robert J., Sitter, Barbara J., Stewart, Andrew Morgan, Szeliga, Jan, Weisenburger, Gerald A.

Journal:

Organic Process Research & Development

Year:

2019

Language:

english

File:

PDF, 1.17 MB

english, 2019